Balancing the application of active learning techniques with content coverage can often pose an instructional challenge. An impactful strategy to incorporate the two is to use figures from primary sources in the classroom. In this interactive workshop, participants will explore strategies for using a primary source figure, and associated resources from HHMI BioInteractive, that allow students to practice their data interpretation skills and generate questions. These also allow students to apply content knowledge such as intrinsic antibiotic resistance in gram negative and gram positive bacteria.