To engage diverse learners, we often look for methods beyond didactic lectures. Particularly for complex biological processes, incorporating learner-centered strategies often seems to require significant time and efforts that neither instructors nor students have. In this microbrew, attendees will participate in a live re-enactment of bacterial peptidoglycan synthesis. As part of this re-enactment, attendees will also act out the mechanisms of antimicrobials that target the peptidoglycan structure as well as the common resistance mechanisms.This engagement practice allows students, both of those re-enacting and those observing, to visualize a complex process and develop critical thinking skills to make predictions on interruptions on the process with real-world relevance and applications. Moreover, this engagement strategy is easily adaptable and customizable for all instructors and learners.