The MEGA-plate (Microbial Evolution and Growth Arena) experiment provides an elegant visual demonstration of bacteria rapidly developing antibiotic resistance. A short video describing the method and major results has already proven useful in the classroom. We have developed a set of curricular materials to connect details of the methods and results of the MEGA-plate experiment and antibiotic resistance to core microbiological concepts. These materials enhance the use of the video by providing important foundations before showing students the video, facilitating discussion of the video, and engaging students with deeper concepts and skills from the MEGA-plate research article, following the video.
